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Absence of Mutations in marRAB or soxRS in acrB-Overexpressing Fluoroquinolone-Resistant Clinical and Veterinary Isolates of Escherichia coli

The amount of acrB, marA, and soxS mRNA was determined in 36 fluoroquinolone-resistant E. coli from humans and animals, 27 of which displayed a multiple-resistance phenotype. acrB mRNA was elevated in 11 of 36 strains. A mutation at codon 45 (Arg→Cys) in acrR was found in 6 of these 11 strains. Ten...

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Detalhes bibliográficos
Main Authors: Webber, Mark A., Piddock, Laura J. V.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC90504/
https://ncbi.nlm.nih.gov/pubmed/11302826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.5.1550-1552.2001
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