Absence of Mutations in marRAB or soxRS in acrB-Overexpressing Fluoroquinolone-Resistant Clinical and Veterinary Isolates of Escherichia coli

The amount of acrB, marA, and soxS mRNA was determined in 36 fluoroquinolone-resistant E. coli from humans and animals, 27 of which displayed a multiple-resistance phenotype. acrB mRNA was elevated in 11 of 36 strains. A mutation at codon 45 (Arg→Cys) in acrR was found in 6 of these 11 strains. Ten...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Webber, Mark A., Piddock, Laura J. V.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2001
Assuntos:	Mechanisms of Resistance
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90504/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11302826/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.45.5.1550-1552.2001
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