Inhibitory Activities of Lansoprazole against Respiration in Helicobacter pylori

Lansoprazole and its derivative AG-1789 dose-dependently inhibited cellular respiration by an endogenous substrate and decreased the ATP level in Helicobacter pylori cells. The inhibitory action of lansoprazole and AG-1789 against respiration was specific to substrates such as pyruvate and α-ketoglu...

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Bibliographic Details
Main Authors: Nagata, Kumiko, Sone, Nobuhito, Tamura, Toshihide
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2001
Subjects:
Mechanisms of Action: Physiological Effects
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC90499/
https://ncbi.nlm.nih.gov/pubmed/11302821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.5.1522-1527.2001
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