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Amphotericin B Lipid Complex or Amphotericin B Multiple-Dose Administration to Rabbits with Elevated Plasma Cholesterol Levels: Pharmacokinetics in Plasma and Blood, Plasma Lipoprotein Levels, Distribution in Tissues, and Renal Toxicities

The purpose of the present study was to determine if a relationship exists between the plasma cholesterol concentration, the severity of amphotericin B (AmpB)-induced renal toxicity, and the pharmacokinetics of AmpB in plasma in hypercholesterolemic rabbits administered multiple doses of amphoterici...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Principais autores: Ramaswamy, Manisha, Peteherych, Kathy D., Kennedy, Allison L., Wasan, Kishor M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2001
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90442/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11257033/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.45.4.1184-1191.2001
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