Comparison of the Anti-Influenza Virus Activity of RWJ-270201 with Those of Oseltamivir and Zanamivir

We have recently reported an influenza virus neuraminidase inhibitor, RWJ-270201 (BCX-1812), a novel cyclopentane derivative discovered through structure-based drug design. In this paper, we compare the potency of three compounds, RWJ-270201, oseltamivir, and zanamivir, against neuraminidase enzymes...

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Main Authors: Bantia, S., Parker, C. D., Ananth, S. L., Horn, L. L., Andries, K., Chand, P., Kotian, P. L., Dehghani, A., El-Kattan, Y., Lin, T., Hutchison, T. L., Montgomery, J. A., Kellog, D. L., Babu, Y. S.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2001
Assuntos:
Antiviral Agents
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC90439/
https://ncbi.nlm.nih.gov/pubmed/11257030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.4.1162-1167.2001
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