Comparison of Efficacies of Cysteine Protease Inhibitors against Five Strains of Plasmodium falciparum

Falcipain-2, a cysteine protease and essential hemoglobinase of Plasmodium falciparum, is a potential antimalarial drug target. We compared the falcipain-2 sequences and sensitivities to cysteine protease inhibitors of five parasite strains that differ markedly in sensitivity to established antimala...

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Autores principales: Singh, Ajay, Rosenthal, Philip J.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2001
Materias:
Susceptibility
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC90401/
https://ncbi.nlm.nih.gov/pubmed/11181388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.3.949-951.2001
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