Prevalence and Conditions of Selection of E44D/A and V118I Human Immunodeficiency Virus Type 1 Reverse Transcriptase Mutations in Clinical Practice

Recently, it has been shown that a new mutational pattern (the E44D/A and/or V118I mutation) confers moderate phenotypic lamivudine resistance in the absence of the M184V mutation. The E44D/A and/or the V118I mutation does not exist in drug-naive patients, and the prevalence increases with the numbe...

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Hlavní autoři: Delaugerre, Constance, Mouroux, Mireille, Yvon-Groussin, Anne, Simon, Anne, Angleraud, Francis, Huraux, Jean-Marie, Agut, Henri, Katlama, Christine, Calvez, Vincent
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2001
Témata:
Antiviral Agents
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC90400/
https://ncbi.nlm.nih.gov/pubmed/11181387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.3.946-948.2001
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