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Pharmacokinetics of Ethionamide Administered under Fasting Conditions or with Orange Juice, Food, or Antacids

This study was conducted in order to (i) determine the effect of food, orange juice, or antacids on the absorption of a single oral 500-mg dose of ethionamide (ETA) in healthy volunteers, including an assessment of bioequivalence, and (ii) determine ETA population pharmacokinetic (PK) parameters. Th...

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Udgivet i:Antimicrob Agents Chemother
Principais autores: Auclair, Barbara, Nix, David E., Adam, Rodney D., James, Gordon T., Peloquin, Charles A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2001
Fag:
Pharmacology
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90379/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11181366/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.45.3.810-814.2001
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