Pharmacokinetics of Ethionamide Administered under Fasting Conditions or with Orange Juice, Food, or Antacids

This study was conducted in order to (i) determine the effect of food, orange juice, or antacids on the absorption of a single oral 500-mg dose of ethionamide (ETA) in healthy volunteers, including an assessment of bioequivalence, and (ii) determine ETA population pharmacokinetic (PK) parameters. Th...

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Autors principals: Auclair, Barbara, Nix, David E., Adam, Rodney D., James, Gordon T., Peloquin, Charles A.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2001
Matèries:
Pharmacology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC90379/
https://ncbi.nlm.nih.gov/pubmed/11181366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.3.810-814.2001
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