Rapid Detection of Mutations in the Human-Derived Pneumocystis carinii Dihydropteroate Synthase Gene Associated with Sulfa Resistance

Recent studies have shown that point mutations in the dihydropteroate synthase (DHPS) gene of human-derived Pneumocystis carinii are related to exposure to sulfa drugs and possibly represent the emergence of sulfa resistance. We developed a simple single-strand conformation polymorphism (SSCP) metho...

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Bibliographic Details
Main Authors: Ma, Liang, Kovacs, Joseph A.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2001
Subjects:
Mechanisms of Resistance
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC90372/
https://ncbi.nlm.nih.gov/pubmed/11181359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.3.776-780.2001
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