Rapid Detection of Mutations in the Human-Derived Pneumocystis carinii Dihydropteroate Synthase Gene Associated with Sulfa Resistance

Recent studies have shown that point mutations in the dihydropteroate synthase (DHPS) gene of human-derived Pneumocystis carinii are related to exposure to sulfa drugs and possibly represent the emergence of sulfa resistance. We developed a simple single-strand conformation polymorphism (SSCP) metho...

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Detalles Bibliográficos

Publicado en:	Antimicrob Agents Chemother
Principais autores:	Ma, Liang, Kovacs, Joseph A.
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Microbiology (ASM) 2001
Assuntos:	Mechanisms of Resistance
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90372/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11181359/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.45.3.776-780.2001
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