Dynamic and Heterogeneous Mutations to Fluconazole Resistance in Cryptococcus neoformans

Infections with the human pathogenic basidiomycetous yeast Cryptococcus neoformans are often treated with fluconazole. Resistance to this antifungal agent has been reported. This study investigated the patterns of mutation to fluconazole resistance in C. neoformans in vitro. The MIC of fluconazole w...

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Bibliographic Details
Main Authors: Xu, Jianping, Onyewu, Chiatogu, Yoell, Heather J., Ali, Rabia Y., Vilgalys, Rytas J., Mitchell, Thomas G.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2001
Subjects:
Mechanisms of Resistance
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC90307/
https://ncbi.nlm.nih.gov/pubmed/11158735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.2.420-427.2001
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