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Mutation in 23S rRNA Responsible for Resistance to 16-Membered Macrolides and Streptogramins in Streptococcus pneumoniae

Streptococcus pneumoniae clinical isolate BM4455 was resistant to 16-membered macrolides and to streptogramins. This unusual resistance phenotype was due to an A(2062)C (Escherichia coli numbering) mutation in domain V of the four copies of 23S rRNA.

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書目詳細資料
Main Authors: Depardieu, Florence, Courvalin, Patrice
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2001
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC90283/
https://ncbi.nlm.nih.gov/pubmed/11120988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.1.319-323.2001
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