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In Vitro and In Vivo Efficacies of T-3811ME (BMS-284756) against Mycoplasma pneumoniae

T-3811, the free base of T-3811ME (BMS-284756), a new des-F(6)-quinolone, showed a potent in vitro activity (MIC at which 90% of the isolates tested are inhibited [MIC(90)], 0.0313 μg/ml) against Mycoplasma pneumoniae. The MIC(90) of T-3811 was 4-fold higher than that of clarithromycin but was 4- to...

Celý popis

Uloženo v:
Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: Takahata, Masahiro, Shimakura, Masako, Hori, Ritsuko, Kizawa, Kazuo, Todo, Yozo, Minami, Shinzaburo, Watanabe, Yasuo, Narita, Hirokazu
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2001
Témata:
Experimental Therapeutics
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90281/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11120986/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.45.1.312-315.2001
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