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If Taken 1 Hour before Indinavir (IDV), Didanosine Does Not Affect IDV Exposure, despite Persistent Buffering Effects

Concurrent administration of indinavir and didanosine significantly reduces the level of exposure to indinavir, but it is unclear how soon after didanosine administration indinavir may be given safely. We compared indinavir pharmacokinetics and gastric pH in 12 human immunodeficiency virus-positive...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: Shelton, Mark J., Mei, Haijing, Hewitt, Ross G., Defrancesco, Robin
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2001
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90276/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11120981/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.45.1.298-300.2001
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