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Antiretroviral Agents Inhibit Infection of Human Cells by Porcine Endogenous Retroviruses

The efficacy of antiretroviral drugs against porcine endogenous retroviruses (PERV) that may be harbored in pig organs intended for transplantation was examined in human cells in vitro. The nucleoside analogs zidovudine and dideoxyinosine were found to effectively inhibit PERV replication.

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Publicado no:Antimicrob Agents Chemother
Principais autores: Powell, S. K., Gates, M. E., Langford, G., Gu, M.-L., Lockey, C., Long, Z., Otto, E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2000
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90217/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11083652/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.44.12.3432-3433.2000
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