Deregulation of the Arginine Deiminase (arc) Operon in Penicillin-Tolerant Mutants of Streptococcus gordonii

Penicillin tolerance is an incompletely understood phenomenon that allows bacteria to resist drug-induced killing. Tolerance was studied with independent Streptococcus gordonii mutants generated by cyclic exposure to 500 times the MIC of penicillin. Parent cultures lost 4 to 5 log(10) CFU/ml of viab...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Caldelari, I., Loeliger, B., Langen, H., Glauser, M. P., Moreillon, P.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2000
Soggetti:	Mechanisms of Resistance
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90154/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10991863/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.44.10.2802-2810.2000
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