Comparison of a New Triazole, Posaconazole, with Itraconazole and Amphotericin B for Treatment of Histoplasmosis following Pulmonary Challenge in Immunocompromised Mice

A murine model of intratracheally induced histoplasmosis in immunocompromised B6C3F(1) mice was used to evaluate a new triazole antifungal agent, posaconazole. This compound was previously shown to be comparable to amphotericin B and superior to itraconazole for the treatment of histoplasmosis in im...

Ausführliche Beschreibung

Bibliografische Detailangaben

Veröffentlicht in:	Antimicrob Agents Chemother
Hauptverfasser:	Connolly, Patricia, Wheat, L. Joseph, Schnizlein-Bick, Carol, Durkin, Michelle, Kohler, Steve, Smedema, Melinda, Goldberg, Janet, Brizendine, Edward, Loebenberg, David
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 2000
Schlagworte:	Experimental Therapeutics
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90122/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10991831/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.44.10.2604-2608.2000
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