Molecular Characterization of the Plasma Membrane H(+)-ATPase, an Antifungal Target in Cryptococcus neoformans

The Cryptococcus neoformans PMA1 gene, encoding a plasma membrane H(+)-ATPase, was isolated from a genomic DNA library of serotype A strain ATCC 6352. An open reading frame of 3,380 nucleotides contains six introns and encodes a predicted protein consisting of 998 amino acids with a molecular mass o...

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Main Authors: Soteropoulos, Patricia, Vaz, Tanya, Santangelo, Rosaria, Paderu, Padmaja, Huang, David Y., Tamás, Markus J., Perlin, David S.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2000
Teme:
Mechanisms of Action: Physiological Effects
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC90068/
https://ncbi.nlm.nih.gov/pubmed/10952578
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