In Vitro Antimicrobial Activities of Novel Anilinouracils Which Selectively Inhibit DNA Polymerase III of Gram-Positive Bacteria

The 6-anilinouracils are novel dGTP analogs that selectively inhibit the replication-specific DNA polymerase III of gram-positive eubacteria. Two specific derivatives, IMAU (6-[3′-iodo-4′-methylanilino]uracil) and EMAU (6-[3′-ethyl-4′-methylanilino]uracil), were substituted with either a hydroxybuty...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Daly, Jennifer S., Giehl, Theodore J., Brown, Neal C., Zhi, Chengxin, Wright, George E., Ellison, Richard T.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2000
Assuntos:	Susceptibility
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90046/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10898708/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.44.8.2217-2221.2000
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