Mechanism of Metronidazole Resistance in Helicobacter pylori: Comparison of the rdxA Gene Sequences in 30 Strains

The rdxA gene of 30 independently isolated Helicobacter pylori strains was sequenced. A comparison of the rdxA sequences revealed a higher percentage of amino acid substitutions in the corresponding protein than in other housekeeping genes. Out of 122 point mutations, 41 were missense and 4 were non...

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Veröffentlicht in:	Antimicrob Agents Chemother
Hauptverfasser:	Solcà, Nadia Maggi, Bernasconi, Marco Valerio, Piffaretti, Jean-Claude
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 2000
Schlagworte:	Mechanisms of Resistance
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90043/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10898705/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.44.8.2207-2210.2000
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