In Vitro Reversion of Amphotericin B Resistance in Leishmania donovani by Poloxamer 188

A micellar formulation of amphotericin B (AmB) solubilized with poloxamer 188 was evaluated against an AmB Leishmania donovani-resistant line. A concave isobologram showed a synergistic effect of this association against promastigotes. This result was confirmed with amastigotes since the 50% effecti...

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Publié dans:	Antimicrob Agents Chemother
Auteurs principaux:	Espuelas, S., Legrand, P., Loiseau, P. M., Bories, C., Barratt, G., Irache, J. M.
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 2000
Sujets:	Susceptibility
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90038/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10898700/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.44.8.2190-2192.2000
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