In Vitro Reversion of Amphotericin B Resistance in Leishmania donovani by Poloxamer 188

A micellar formulation of amphotericin B (AmB) solubilized with poloxamer 188 was evaluated against an AmB Leishmania donovani-resistant line. A concave isobologram showed a synergistic effect of this association against promastigotes. This result was confirmed with amastigotes since the 50% effecti...

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Bibliografski detalji
Glavni autori: Espuelas, S., Legrand, P., Loiseau, P. M., Bories, C., Barratt, G., Irache, J. M.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2000
Teme:
Susceptibility
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC90038/
https://ncbi.nlm.nih.gov/pubmed/10898700
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