Role of Putative Loops 2 and 3 in Imipenem Passage through the Specific Porin OprD of Pseudomonas aeruginosa

Mutant proteins with eight amino acid deletions in putative surface loops 2 and 3 of the imipenem-specific porin OprD of Pseudomonas aeruginosa failed to reconstitute imipenem susceptibility in an oprD-deficient background. The loop 3 deletion prevented the ability of imipenem to inhibit KCl conduct...

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Veröffentlicht in:	Antimicrob Agents Chemother
Hauptverfasser:	Ochs, Martina M., Bains, Manjeet, Hancock, Robert E. W.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 2000
Schlagworte:	Mechanisms of Action: Physiological Effects
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89998/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10858367/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.44.7.1983-1985.2000
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