Comparison of the Echinocandin Caspofungin with Amphotericin B for Treatment of Histoplasmosis following Pulmonary Challenge in a Murine Model

Twenty clinical isolates of Histoplasma capsulatum were tested for their in vitro susceptibilities to caspofungin in comparison to those to amphotericin B by following National Committee for Clinical Laboratory Standards guidelines for yeasts. The mean MICs were 16.6 μg/ml (range, 8 to 32 μg/ml) for...

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Bibliographische Detailangaben
Hauptverfasser: Kohler, Steve, Wheat, L. Joseph, Connolly, Patricia, Schnizlein-Bick, Carol, Durkin, Michelle, Smedema, Melinda, Goldberg, Janet, Brizendine, Edward
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2000
Schlagworte:
Experimental Therapeutics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC89973/
https://ncbi.nlm.nih.gov/pubmed/10858342
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