Roles of gyrA Mutations in Resistance of Clinical Isolates and In Vitro Mutants of Bacteroides fragilis to the New Fluoroquinolone Trovafloxacin

We determined whether gyrA mutations were present in fluoroquinolone-resistant laboratory mutants derived from the Bacteroides fragilis reference strain ATCC 25285 and in clinical isolates of B. fragilis. The two first-step mutants selected on ciprofloxacin (CIP) were devoid of gyrA mutations, where...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Bachoual, Rafik, Dubreuil, Luc, Soussy, Claude-James, Tankovic, Jacques
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2000
Assuntos:	Mechanisms of Resistance
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89971/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10858340/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.44.7.1842-1845.2000
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