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Inhibitors of Sterol Biosynthesis and Amphotericin B Reduce the Viability of Pneumocystis carinii f. sp. carinii

Pneumocystis carinii synthesizes sterols with a double bond at C-7 of the sterol nucleus and an alkyl group with one or two carbons at C-24 of the side chain. Also, some human-derived Pneumocystis carinii f. sp. hominis strains contain lanosterol derivatives with an alkyl group at C-24. These unique...

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Bibliografske podrobnosti
Main Authors: Kaneshiro, Edna S., Collins, Margaret S., Cushion, Melanie T.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2000
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC89924/
https://ncbi.nlm.nih.gov/pubmed/10817720
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