Biochemical-Genetic Characterization and Regulation of Expression of an ACC-1-Like Chromosome-Borne Cephalosporinase from Hafnia alvei

A naturally occurring AmpC β-lactamase (cephalosporinase) gene was cloned from the Hafnia alvei 1 clinical isolate and expressed in Escherichia coli. The deduced AmpC β-lactamase (ACC-2) had a pI of 8 and a relative molecular mass of 37 kDa and showed 50 and 47% amino acid identity with the chromoso...

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Veröffentlicht in:	Antimicrob Agents Chemother
Hauptverfasser:	Girlich, Delphine, Naas, Thierry, Bellais, Samuel, Poirel, Laurent, Karim, Amal, Nordmann, Patrice
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 2000
Schlagworte:	Mechanisms of Resistance
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89899/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10817695/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.44.6.1470-1478.2000
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