Evidence for the Existence of a Multidrug Efflux Transporter Distinct from NorA in Staphylococcus aureus

A Staphylococcus aureus norA disruption mutant was created by allelic replacement. Exposure of this mutant to norfloxacin produced SA K1748, a derivative with raised fluoroquinolone MICs, found to be the result of a grlA mutation, and raised organic cation MICs. Ethidium and enoxacin uptake was iden...

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Bibliographic Details
Main Authors: Kaatz, Glenn W., Seo, Susan M., O'Brien, Louise, Wahiduzzaman, Mohammad, Foster, Timothy J.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2000
Subjects:
Mechanisms of Resistance
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC89884/
https://ncbi.nlm.nih.gov/pubmed/10770791
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