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Contributions of the AmpC β-Lactamase and the AcrAB Multidrug Efflux System in Intrinsic Resistance of Escherichia coli K-12 to β-Lactams

The roles of the AmpC chromosomal β-lactamase and the AcrAB efflux system in levels of intrinsic resistance and susceptibility of Escherichia coli to β-lactams were studied with a set of isogenic strains. MICs of ureidopenicillins, carbenicillin, oxacillin, and cloxacillin were drastically reduced b...

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Publicat a:Antimicrob Agents Chemother
Autors principals: Mazzariol, Annarita, Cornaglia, Giuseppe, Nikaido, Hiroshi
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2000
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89880/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10770787/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.44.5.1387-1390.2000
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