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Contributions of the AmpC β-Lactamase and the AcrAB Multidrug Efflux System in Intrinsic Resistance of Escherichia coli K-12 to β-Lactams

The roles of the AmpC chromosomal β-lactamase and the AcrAB efflux system in levels of intrinsic resistance and susceptibility of Escherichia coli to β-lactams were studied with a set of isogenic strains. MICs of ureidopenicillins, carbenicillin, oxacillin, and cloxacillin were drastically reduced b...

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Bibliografiske detaljer
Main Authors: Mazzariol, Annarita, Cornaglia, Giuseppe, Nikaido, Hiroshi
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2000
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC89880/
https://ncbi.nlm.nih.gov/pubmed/10770787
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