Syringomycin E Inhibition of Saccharomyces cerevisiae: Requirement for Biosynthesis of Sphingolipids with Very-Long-Chain Fatty Acids and Mannose- and Phosphoinositol-Containing Head Groups

Syringomycin E is an antifungal cyclic lipodepsinonapeptide that inhibits the growth of Saccharomyces cerevisiae by interaction with the plasma membrane. A screen conducted to find the yeast genes necessary for its fungicidal action identified two novel syringomycin E response genes, SYR3 and SYR4....

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Veröffentlicht in:	Antimicrob Agents Chemother
Hauptverfasser:	Stock, Stephen D., Hama, Hiroko, Radding, Jeffrey A., Young, Debra A., Takemoto, Jon Y.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 2000
Schlagworte:	Mechanisms of Action: Physiological Effects
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89841/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10770748/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.44.5.1174-1180.2000
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