Towards an Understanding of the Mechanism of Pyrimethamine-Sulfadoxine Resistance in Plasmodium falciparum: Genotyping of Dihydrofolate Reductase and Dihydropteroate Synthase of Kenyan Parasites
The antifolate combination of pyrimethamine (PM) and sulfadoxine (SD) is the last affordable drug combination available for wide-scale treatment of falciparum malaria in Africa. Wherever this combination has been used, drug-resistant parasites have been selected rapidly. A study of PM-SD effectivene...
Sparad:
| I publikationen: | Antimicrob Agents Chemother |
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| Huvudupphov: | , , , , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Utgiven: |
American Society for Microbiology (ASM)
2000
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89803/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10722502/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.44.4.991-996.2000 |
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