Pefloxacin-Induced Achilles Tendon Toxicity in Rodents: Biochemical Changes in Proteoglycan Synthesis and Oxidative Damage to Collagen

Despite a relatively low incidence of serious side effects, fluoroquinolones and the fluoroquinolone pefloxacin have been reported to occasionally promote tendinopathy that might result in the complication of spontaneous rupture of tendons. In the present study, we investigated in rodents the intrin...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Simonin, Marie-Agnes, Gegout-Pottie, Pascale, Minn, Alain, Gillet, Pierre, Netter, Patrick, Terlain, Bernard
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2000
Assuntos:	Pharmacology
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89784/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10722483/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.44.4.867-872.2000
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