Frequent Association between Alteration of the rdxA Gene and Metronidazole Resistance in French and North African Isolates of Helicobacter pylori

Mutations in the rdxA gene have been associated with the acquisition of resistance to metronidazole in Helicobacter pylori. This gene encodes an NADPH nitroreductase whose expression is necessary for intracellular activation of the drug. We wished to examine whether mutations in rdxA were present in...

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書誌詳細

出版年:	Antimicrob Agents Chemother
主要な著者:	Tankovic, Jacques, Lamarque, Dominique, Delchier, Jean-Charles, Soussy, Claude-James, Labigne, Agnes, Jenks, Peter J.
フォーマット:	Artigo
言語:	Inglês
出版事項:	American Society for Microbiology (ASM) 2000
主題:	Mechanisms of Resistance
オンライン･アクセス:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89734/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10681326/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.44.3.608-613.2000
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