A Dose Ranging Study of the Pharmacokinetics, Safety, and Preliminary Efficacy of Lamivudine in Children and Adolescents with Chronic Hepatitis B

Fifty-three patients with chronic hepatitis B and active viral replication were studied for 4 weeks while on treatment and for 12 weeks after treatment with the oral nucleoside analogue lamivudine. Children aged 2 to 12 years were randomized to receive twice-daily doses of 0.35, 1.5, or 4 mg of lami...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Sokal, Etienne M., Roberts, Eve A., Mieli-Vergani, Giorgina, McPhillips, Penny, Johnson, Mark, Barber, Judy, Dallow, Nigel, Boxall, Elizabeth, Kelly, Deirdre
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2000
Assuntos:	Antiviral Agents
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89731/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10681323/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.44.3.590-597.2000
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