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Efficacy of Liposomal Amphotericin B with Prolonged Circulation in Blood in Treatment of Severe Pulmonary Aspergillosis in Leukopenic Rats

The therapeutic efficacy of long-circulating polyethylene glycol-coated liposomal amphotericin B (AMB) (PEG-AMB-LIP) was compared with that of AMB desoxycholate (Fungizone) in a model of severe invasive pulmonary aspergillosis in persistently leukopenic rats as well as in temporarily leukopenic rats...

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Bibliographic Details
Main Authors: Van Etten, Els W. M., Stearne-Cullen, Lorna E. T., Ten Kate, Marian T., Bakker-Woudenberg, Irma A. J. M.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2000
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC89723/
https://ncbi.nlm.nih.gov/pubmed/10681315
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