Prevalence of gyrA, gyrB, parC, and parE Mutations in Clinical Isolates of Streptococcus pneumoniae with Decreased Susceptibilities to Different Fluoroquinolones and Originating from Worldwide Surveillance Studies during the 1997-1998 Respiratory Season

From 8,419 worldwide clinical isolates of Streptococcus pneumoniae obtained during 1997-1998, 69 isolates with reduced susceptibility or resistance to fluoroquinolones (FQs) were molecularly characterized. For the isolates in this prevalence study, only parC (Ser-79→Tyr) and gyrA (Ser-81→Phe or Tyr)...

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Veröffentlicht in:	Antimicrob Agents Chemother
Hauptverfasser:	Jones, Mark E., Sahm, Daniel F., Martin, Nele, Scheuring, Sibylle, Heisig, Peter, Thornsberry, Clyde, Köhrer, Karl, Schmitz, Franz-Josef
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 2000
Schlagworte:	Mechanisms of Resistance
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89708/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10639387/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.44.2.462-466.2000
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