Prevalence of gyrA, gyrB, parC, and parE Mutations in Clinical Isolates of Streptococcus pneumoniae with Decreased Susceptibilities to Different Fluoroquinolones and Originating from Worldwide Surveillance Studies during the 1997-1998 Respiratory Season

From 8,419 worldwide clinical isolates of Streptococcus pneumoniae obtained during 1997-1998, 69 isolates with reduced susceptibility or resistance to fluoroquinolones (FQs) were molecularly characterized. For the isolates in this prevalence study, only parC (Ser-79→Tyr) and gyrA (Ser-81→Phe or Tyr)...

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Autores principales: Jones, Mark E., Sahm, Daniel F., Martin, Nele, Scheuring, Sibylle, Heisig, Peter, Thornsberry, Clyde, Köhrer, Karl, Schmitz, Franz-Josef
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2000
Materias:
Mechanisms of Resistance
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC89708/
https://ncbi.nlm.nih.gov/pubmed/10639387
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