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In Vitro Activities of Rabeprazole, a Novel Proton Pump Inhibitor, and Its Thioether Derivative Alone and in Combination with Other Antimicrobials against Recent Clinical Isolates of Helicobacter pylori

The MICs of rabeprazole sodium (RPZ), a newly developed benzimidazole proton pump inhibitor (PPI), against 133 clinical Helicobacter pylori strains revealed a higher degree of activity than the another two PPIs, lansoprazole and omeprazole. Time-kill curve assays of RPZ, when combined with amoxicill...

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Udgivet i:Antimicrob Agents Chemother
Principais autores: Kawakami, Yoshiyuki, Akahane, Takayuki, Yamaguchi, Masaru, Oana, Kozue, Takahashi, Yuko, Okimura, Yukie, Okabe, Tadashi, Gotoh, Akira, Katsuyama, Tsutomu
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2000
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Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89707/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10639386/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.44.2.458-461.2000
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