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Bioavailability of Aciclovir after Oral Administration of Aciclovir and Its Prodrug Valaciclovir to Patients with Leukopenia after Chemotherapy

The median bioavailabilities of aciclovir after administration of aciclovir and its prodrug valaciclovir were 21.5 and 70.1%, respectively, in 12 patients with malignant hematological diseases with leukopenia after chemotherapy. The interindividual variations of the bioavailability were 48.5 and 21....

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Publicat a:Antimicrob Agents Chemother
Autors principals: Steingrimsdottir, Hlif, Gruber, Astrid, Palm, Carina, Grimfors, Gunnar, Kalin, Mats, Eksborg, Staffan
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2000
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Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89657/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10602752/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.44.1.207-209.2000
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