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Persistence of Infectious Herpes Simplex Virus Type 2 in the Nervous System in Mice after Antiviral Chemotherapy

Young adult mice were inoculated with herpes simplex virus type 2 (HSV-2) in the ear pinna. A relatively severe infection resulted, and 45% of the mice died by 11 days postinfection. Therapy at 1 mg/ml by means of the drinking water with either famciclovir for periods of 5 or 10 days or valaciclovir...

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Autores principales: Thackray, Alana M., Field, Hugh J.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2000
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC89634/
https://ncbi.nlm.nih.gov/pubmed/10602729
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