Oral Bioavailability and Pharmacokinetics of Trovafloxacin in Patients with AIDS

Trovafloxacin pharmacokinetics were evaluated in 12 subjects with AIDS. By using a randomized design, single 200-mg doses of oral trovafloxacin and intravenous alatrofloxacin were administered. The mean absolute bioavailability was 91%. The pharmacokinetics of trovafloxacin when administered orally...

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Bibliographic Details
Main Authors: Lacy, Melinda K., Nicolau, David P., Nightingale, Charles H., Geffken, Amy, Teng, Renli, Vincent, John, Quintiliani, Richard
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1999
Subjects:
Pharmacology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC89603/
https://ncbi.nlm.nih.gov/pubmed/10582898
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