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Activities of the Oxazolidinones Linezolid and Eperezolid in Experimental Intra-Abdominal Abscess Due to Enterococcus faecalis or Vancomycin-Resistant Enterococcus faecium

The in vivo effectiveness of oxazolidinones eperezolid (U-100592) and linezolid (U-100766) against one strain each of Enterococcus faecalis and vancomycin-resistant Enterococcus faecium was examined in a rat model of intra-abdominal abscess. MICs of both drugs were 2 μg/ml for each strain. At doses...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Principais autores: Schülin, T., Thauvin-Eliopoulos, C., Moellering, R. C., Eliopoulos, G. M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1999
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89579/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10582874/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.43.12.2873
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