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Competition of Various β-Lactam Antibiotics for the Major Penicillin-Binding Proteins of Helicobacter pylori: Antibacterial Activity and Effects on Bacterial Morphology

The penicillin-binding proteins (PBPs) of helical (log-phase) Helicobacter pylori ATCC 43579 were identified by using biotinylated ampicillin. The major PBPs had apparent molecular masses of 47, 60, 63, and 66 kDa; an additional minor PBP of 95 to 100 kDa was also detected. The relative affinities o...

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Udgivet i:Antimicrob Agents Chemother
Principais autores: DeLoney, Cindy R., Schiller, Neal L.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1999
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Mechanisms of Action: Physiological Effects
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89546/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10543750/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.43.11.2702
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