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Chemoprophylaxis of Influenza A Virus Infections, with Single Doses of Zanamivir, Demonstrates that Zanamivir Is Cleared Slowly from the Respiratory Tract

Zanamivir (4-guanidino-2,4-dideoxy-2,3-dehydro-N-acetylneuraminic acid; Relenza; GG167) is a potent and highly specific neuraminidase (sialidase) inhibitor with inhibitory activity in vivo against both influenza A and B viruses. This compound has been extensively tested in both mouse and ferret mode...

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Détails bibliographiques
Auteurs principaux: Fenton, Robert J., Morley, Peter J., Owens, Ian J., Gower, David, Parry, Simon, Crossman, Lee, Wong, Tony
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 1999
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC89537/
https://ncbi.nlm.nih.gov/pubmed/10543741
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