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Kinetics of Antiviral Activity and Intracellular Pharmacokinetics of Human Immunodeficiency Virus Type 1 Protease Inhibitors in Tissue Culture

We have examined the kinetics of the inhibition of human immunodeficiency virus type 1 (HIV-1) particle infectivity by protease inhibitors (PIs) in cell culture, using either transfected HeLa cells or infected peripheral blood mononuclear cells (PBMCs) as producers of infectious virions. Both the ki...

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Bibliografski detalji
Izdano u:Antimicrob Agents Chemother
Glavni autori: Nascimbeni, Michelina, Lamotte, Claire, Peytavin, Gilles, Farinotti, Robert, Clavel, François
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 1999
Teme:
Online pristup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89535/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10543739/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.43.11.2629
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