The New Ketolide HMR3647 Accumulates in the Azurophil Granules of Human Polymorphonuclear Cells

HMR3647 is a semisynthetic representative of a new group of drugs, the ketolides, derived from erythromycin A. Since macrolides have been shown to accumulate in human polymorphonuclear cells (PMNs), we have investigated the ability of the molecule HMR3647 to enter human PMNs as well as other cell ty...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Miossec-Bartoli, Christine, Pilatre, Lydie, Peyron, Pascale, N’Diaye, Elsa-Noah, Collart-Dutilleul, Véronique, Maridonneau-Parini, Isabelle, Diu-Hercend, Anita
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1999
Assuntos:	Pharmacology
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89500/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10508024/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.43.10.2457
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