Killing Activities of Trovafloxacin Alone and in Combination with β-Lactam Agents, Rifampin, or Vancomycin against Streptococcus pneumoniae Isolates with Various Susceptibilities to Extended-Spectrum Cephalosporins at Concentrations Clinically Achievable in Cerebrospinal Fluid

The killing activities of trovafloxacin alone and in combination with β-lactam agents (extended-spectrum cephalosporins, meropenem), rifampin, or vancomycin were evaluated against 20 genotypically characterized Streptococcus pneumoniae isolates for which amoxicillin MICs were ≥4 μg/ml (cefotaxime MI...

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Veröffentlicht in:	Antimicrob Agents Chemother
Hauptverfasser:	Fitoussi, Frederic, Doit, Catherine, Geslin, Pierre, Bingen, Edouard
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1999
Schlagworte:	Susceptibility
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89485/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10508009/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.43.10.2372
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