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Pharmacokinetics and Safety of High-Dose and Extended-Interval Regimens of Levofloxacin in Human Immunodeficiency Virus-Infected Patients

The pharmacokinetics of levofloxacin, administered in high doses and with extended dosing intervals, was studied in human immunodeficiency virus (HIV)-infected patients. Thirty patients received either 750 mg of the drug or a placebo once daily for 14 days, followed by 750 mg or 1,000 mg of the drug...

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Udgivet i:Antimicrob Agents Chemother
Principais autores: Piscitelli, Stephen C., Spooner, Katherine, Baird, Barbara, Chow, Andrew T., Fowler, Cynthia L., Williams, Rex R., Natarajan, Jaya, Masur, Henry, Walker, Robert E.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1999
Fag:
Pharmacology
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89473/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10471591/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.43.9.2323
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