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Effective Treatment of Acute and Chronic Murine Tuberculosis with Liposome-Encapsulated Clofazimine

The therapeutic efficacy of liposomal clofazimine (L-CLF) was studied in mice infected with Mycobacterium tuberculosis Erdman. Groups of mice were treated with either free clofazimine (F-CLF), L-CLF, or empty liposomes twice a week for five treatments beginning on day 1 (acute), day 21 (established)...

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Detalhes bibliográficos
Main Authors: Adams, Linda B., Sinha, Indu, Franzblau, Scott G., Krahenbuhl, James L., Mehta, Reeta T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC89336/
https://ncbi.nlm.nih.gov/pubmed/10390215
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