Effective Treatment of Acute and Chronic Murine Tuberculosis with Liposome-Encapsulated Clofazimine

The therapeutic efficacy of liposomal clofazimine (L-CLF) was studied in mice infected with Mycobacterium tuberculosis Erdman. Groups of mice were treated with either free clofazimine (F-CLF), L-CLF, or empty liposomes twice a week for five treatments beginning on day 1 (acute), day 21 (established)...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Adams, Linda B., Sinha, Indu, Franzblau, Scott G., Krahenbuhl, James L., Mehta, Reeta T.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1999
Assuntos:	Experimental Therapeutics
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89336/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10390215/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.43.7.1638
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