Identification and Analysis of the Balhimycin Biosynthetic Gene Cluster and Its Use for Manipulating Glycopeptide Biosynthesis in Amycolatopsis mediterranei DSM5908

Seven complete genes and one incomplete gene for the biosynthesis of the glycopeptide antibiotic balhimycin were isolated from the producer, Amycolatopsis mediterranei DSM5908, by a reverse-cloning approach and characterized. Using oligonucleotides derived from glycosyltransferase sequences, a 900-b...

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Bibliographic Details
Main Authors: Pelzer, S., Süßmuth, R., Heckmann, D., Recktenwald, J., Huber, P., Jung, G., Wohlleben, W.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1999
Subjects:
Chemistry; Biosynthesis
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC89325/
https://ncbi.nlm.nih.gov/pubmed/10390204
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