Activity of Moxifloxacin, Administered Once a Day, against Streptococcus pneumoniae in an In Vitro Pharmacodynamic Model of Infection

The antibacterial effect of moxifloxacin was studied by using an in vitro pharmacodynamic model of infection with dosing simulations of 400 mg every 24 h for 48 h. Streptococcus pneumoniae was tested by using four wild-type strains for which the moxifloxacin MICs were 0.008, 0.12, 0.14, and 3.6 mg/l...

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Veröffentlicht in:	Antimicrob Agents Chemother
Hauptverfasser:	MacGowan, Alasdair P., Bowker, Karen E., Wootton, Mandy, Holt, H. Alan
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1999
Schlagworte:	Pharmacology
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89324/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10390203/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.43.7.1560
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