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Activity of Moxifloxacin, Administered Once a Day, against Streptococcus pneumoniae in an In Vitro Pharmacodynamic Model of Infection

The antibacterial effect of moxifloxacin was studied by using an in vitro pharmacodynamic model of infection with dosing simulations of 400 mg every 24 h for 48 h. Streptococcus pneumoniae was tested by using four wild-type strains for which the moxifloxacin MICs were 0.008, 0.12, 0.14, and 3.6 mg/l...

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Bibliographic Details
Main Authors: MacGowan, Alasdair P., Bowker, Karen E., Wootton, Mandy, Holt, H. Alan
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1999
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC89324/
https://ncbi.nlm.nih.gov/pubmed/10390203
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