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Prospective Evaluation of the Effect of an Aminoglycoside Dosing Regimen on Rates of Observed Nephrotoxicity and Ototoxicity

The nephrotoxicity and ototoxicity associated with once-daily versus twice-daily administration of aminoglycosides was assessed in patients with suspected or proven gram-negative bacterial infections in a randomized, double-blind clinical trial. Patients who received therapy for ≥72 h were evaluated...

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Detalhes bibliográficos
Main Authors: Rybak, Michael J., Abate, Betty J., Kang, S. Lena, Ruffing, Michael J., Lerner, Stephen A., Drusano, George L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC89322/
https://ncbi.nlm.nih.gov/pubmed/10390201
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