Characterization and Nucleotide Sequence of a Klebsiella oxytoca Cryptic Plasmid Encoding a CMY-Type β-Lactamase: Confirmation that the Plasmid-Mediated Cephamycinase Originated from the Citrobacter freundii AmpC β-Lactamase

Plasmid pTKH11, originally obtained by electroporation of a Klebsiella oxytoca plasmid preparation into Escherichia coli XAC, expressed a high level of an AmpC-like β-lactamase. The enzyme, designated CMY-5, conferred resistance to extended-spectrum β-lactams in E. coli; nevertheless, the phenotype...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Wu, Shang Wei, Dornbusch, Kathrine, Kronvall, Göran, Norgren, Mari
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1999
Soggetti:	Mechanisms of Resistance
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89277/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10348751/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.43.6.1350
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